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Gastrointestinal adverse events including nausea, vomiting, and diarrhea are common with current GLP-1 agonists, leading some patients to discontinue treatment or fail to reach maximally effective doses

A few days of unpleasant bouts on the toilet while adjusting to GLP-1s are tolerable, but you should be acutely mindful of more serious side effects : Intense stomach pains, even while not on the toilet Dehydration, presented as altered urination, light-headedness, or fatigue Fever Rememberwhile unpleasant, diarrhea is usually manageable at home and does not impact 100% of people taking Ozempic, Wegovy, or Rybelsus

Many travelers report this as the most reliable option for extended trips